Pretty awesome
This is a misanthrope's dream game -- I get to kill ALL HUMAN KIND! The only problem is that it ends up being a little bit one-dimensional for such an expansive, long-playing game. There are plenty of transmission modifiers but only three ways to really infect a country (borders, air, ship). In the next one, I'd like to see more infection routes. Also, the symptoms/resistances should have more of an effect on gameplay. Even with zero symptoms, your disease can be noticed!
Other than that, it's a great game and I am ravening for the sequel.